Quetiapine (Seroquel)

Picture of Risperidone (Risperdal)

About Quetiapine (Seroquel)

Quetiapine (Seroquel) is an oral antipsychotic drug used for treating schizophrenia and bipolar disorder. Although the mechanism of action of quetiapine is unknown, like other anti-psychotics, it inhibits communication between nerves of the brain. It does this by blocking receptors on the nerves for several neurotransmitters, the chemicals that nerves use to communicate with each other. It is thought that its beneficial effect is due to blocking of the dopamine type 2 (D2) and serotonin type 2 (5-HT2) receptors.

As the mildest of all antipsychotics Quetiapine (Seroquel) doesn’t really carry the “antipsychotic” stigma as heavily as the other meds. Quetiapine (Seroquel)

Seroquel may cause tardive dyskinesia, a condition characterized by uncontrollable muscle spasms and twitches in the face and body. This problem can be permanent, and appears to be most common among older adults, especially women.

Usual Side Effects

Constipation
Drowsiness
Stomach upset
Headache
Fatigue

Dizziness
Dry mouth
Blurry vision
Weight gain

Rare Side Effects

Confusion
Stiff muscles
Sweating
Low blood pressure

Trouble swallowing
Fainting
Tremors Tardive Dyskinesia

Dosages

Quetiapine usually is taken two or three times daily. The dose usually is increased slowly over several days or weeks to achieve the desired effect. Quetiapine can be taken with or without food.